Oct 3Liked by Remnant MD

I like your diffuse-but-converging reconceptualization... fits nicely with the metabolic explanation of cancer as arising from chronic cellular dysfunction.

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Apr 9Liked by Remnant MD

Conventional medicine doesnt know the true origin of cancer: the Dirk Hamer Syndrome:


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Apr 8Liked by Remnant MD

I believe there are other important factors, such as food, environmental toxins, and stress. Exercise, sleep, and emotional/spiritual well-being most likely also play a role. Thus, the general and overall health of the body could be the unseen protection, or vulnerability for cancer growth! What do you think?

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This course may be of interest to you

IPAK-EDU Biology of Cancer Unit Links

Units 1 & 2

Course Overview & The Genetics of Cancer


no password

Biology of Cancer Unit 3 - Environmental Factors and GxE

A. Overview and GxE


B. Carcinogens


Unit 3

The Hallmarks of Cancer

Hanahan & Weinberg 2000


Unit 4

Hallmarks of Cancer: The Next Generation


Unit 5

Hanahan & Weinberg 2011 - Hallmarks of Cancer, The Next Generation


Unit 6

Hallmarks Revisited and Addicted to Secretion


Unit 7

Metastasis in Depth


Unit 8

Hallmarks of Cancer and Wound Healing


No password

Unit 9

Hallmarks of Cancer of Unknown Primary


Unit 10

Hallmarks of Cancer - The New Testament


Unit 11

The Hallmarks of Cancer as Ecologically Driven Phenotypes


Unit 12

Breast Cancer


Unit 13

Lung Cancer


Unit 14

Prostate Cancer


Unit 15

Colon and Colorectal Cancer


Unit 16

Pancreatic Cancer


Unit 17

Gastric Cancer


Unit 18

Cancers of the Blood



Unit 19

Skin Cancers

Unit 20

Cancers of the Brain and CNS


2000 1. Hanahan D, Weinberg RA. The hallmarks of cancer. Cell. 2000 Jan 7;100(1):57-70. doi: 10.1016/s0092-8674(00)81683-9. PMID: 10647931.

2011 2. Hanahan D, Weinberg RA. Hallmarks of cancer: the next generation. Cell. 2011 Mar 4;144(5):646-74. doi: 10.1016/j.cell.2011.02.013. PMID: 21376230.

2014 3. Dejeans, N et al. 2014. Addicted to secrete – novel concepts and targets in cancer therapy Trends in Molecular Medicine 20:242-250

2017 4. Fouad YA, Aanei C. Revisiting the hallmarks of cancer. Am J Cancer Res. 2017 May 1;7(5):1016-1036. PMID: 28560055; PMCID: PMC5446472.

2017 5. Baker S, Ali I, Silins I, Pyysalo S, Guo Y, Högberg J, Stenius U, Korhonen A. Cancer Hallmarks Analytics Tool (CHAT): a text mining approach to organize and evaluate scientific literature on cancer. Bioinformatics. 2017 Dec 15;33(24):3973-3981. doi: 10.1093/bioinformatics/btx454. PMID: 29036271; PMCID: PMC5860084.

2020. 6. Meirson T, Gil-Henn H, Samson AO. Invasion and metastasis: the elusive hallmark of cancer. Oncogene. 2020 Feb;39(9):2024-2026. doi: 10.1038/s41388-019-1110-1. Epub 2019 Nov 19. PMID: 31745295.

2020. 7. MacCarthy-Morrogh L, Martin P. The hallmarks of cancer are also the hallmarks of wound healing. Sci Signal. 2020 Sep 8;13(648):eaay8690. doi: 10.1126/scisignal.aay8690. PMID: 32900881.

2020. 8. Rassy E, Assi T, Pavlidis N. Exploring the biological hallmarks of cancer of unknown primary: where do we stand today? Br J Cancer. 2020 Apr;122(8):1124-1132. doi: 10.1038/s41416-019-0723-z. Epub 2020 Feb 11. PMID: 32042068; PMCID: PMC7156745.

2021 9. Senga SS, Grose RP. Hallmarks of cancer-the new testament. Open Biol. 2021 Jan;11(1):200358. doi: 10.1098/rsob.200358. Epub 2021 Jan 20. PMID: 33465324; PMCID: PMC7881179.

2021 10. Somarelli JA. The Hallmarks of Cancer as Ecologically Driven Phenotypes. Front Ecol Evol. 2021 Apr;9:661583. doi: 10.3389/fevo.2021.661583. Epub 2021 Apr 28. PMID: 34703824; PMCID: PMC8544241.

2022 11. Hanahan D. Hallmarks of Cancer: New Dimensions. Cancer Discov. 2022 Jan;12(1):31-46. doi: 10.1158/2159-8290.CD-21-1059. PMID: 35022204.

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Apr 4Liked by Remnant MD

Great perspective. Thank you Sir. I found this interesting (especially in light of your commentary on how cancer has been invaded by genomics)


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Apr 3Liked by Remnant MD

I’ll also eagerly await the next installment before fully commenting other than to ask if you are going to address Warburg and the metabolic theory of cancer?

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Apr 3Liked by Remnant MD

Obviously waiting for the next instalment but (!) have you read The Cancer Code by Jason Fung which proposes the theory that cancer cells are basically a type of reverse evolution ( to behaving the way single celled organisms would). I can’t remember anymore details at the moment but it explained a lot.

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Apr 3·edited Apr 3Liked by Remnant MD

Interesting thought about cells switching behaviors as a group emergence.

A very old neurosurgeon told me a story about a glioblastoma clinical trial that he was involved in. He managed to get one of his patients enrolled -- a teenager with an advanced case. The tumor disappeared. People enrolled in that trial had their tumors evaporate - it was an amazing cure. The scientists behind the trial (I believe it was in Boston) of course wanted to bring this cure to market, but the large pharma who owned this special recipe did a cost-benefit calculation and determined that the price would be too high and the (financial) rewards too few to make it worthwhile.

So rather than publicizing this magic recipe for the whole world to benefit from, they simply didn't proceed with bringing it to market.

As for the teenager who was miraculously cured, he got hit by a car a few years later and died. So I guess he had his timeline pretty set in stone.

This neurosurgeon spent the last years of his life draining his own ascites - advanced liver failure - and continued to serve patients until the day of his death.

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Apr 3Liked by Remnant MD

Yes, the current paradigm is incomplete. Here is why in great detail:

Submolecular Dysregulation Due to Deuterium Accumulation Is the Cause of Cancer.



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