INSIGHTS | 14. Testing the Lipid Energy Model

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Article: Short-Term hyper-caloric high-fat feeding on a ketogenic diet can lower LDL

You may recall from the 7th installment of the Insights Series, that we introduced the Lipid Energy Model put forth by David Feldman and his collaborators. This is a model I am very interested in, because it provides a broader account of the relationship between diet & metabolic health. For this reason, I will be keeping a close eye on its development.

INSIGHTS | 7. Lipid Energy Model of Cholesterol

To summarize, the Lipid Energy Model (LEM) predicts that under low-carb intake (ketogenic diet) the liver can increase the release of triglyceride-rich VLDL (very low density lipoprotein), which is coupled with increased enzymatic activity in the periphery (e.g. muscles) that processes VLDL, and results in increased LDL-C and HDL-C with associated low triglycerides.

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